Leg pain may be caused by physiological reasons, osteoarthritis of the knee, varicose veins of the lower limbs, etc. You can choose general treatment, medication, surgery and other ways of treatment according to different causes. 1. Physiological reasons: long-term walking or running and jumping lead to leg muscle fatigue and injury, causing leg pain. Rest, localized hot compresses and physical therapy can be used to relieve muscle fatigue and thus reduce pain. 2. Osteoarthritis of the knee: Osteoarthritis of the knee can occur due to weather changes, excessive activity, dampness and cold, etc. Oral ibuprofen, celecoxib and other non-steroidal anti-inflammatory drugs can be taken under the guidance of a doctor to relieve pain. 3. Varicose veins of the lower limbs: when the pressure in the veins of patients with varicose veins of the lower limbs is too high, the blood will infiltrate from the walls of the blood vessels to the subcutaneous tissues and cause swelling and pain in the lower limbs. You can wear elastic stockings or use elastic bandage to reduce venous stasis and thus reduce pain; sclerotherapy or surgical ligation of saphenous vein is feasible for those with serious symptoms. The causes of leg pain are many, including trauma, fracture and other reasons, should go to the hospital in time, actively improve the examination, identify the cause of the disease, according to the cause of the targeted treatment.