Cholangiocarcinoma patients can usually have moxibustion; however, due to individual differences, it is recommended to be evaluated by a medical professional. Moxibustion therapy, the most commonly used moxibustion method in Chinese medicine clinics. It refers to a therapeutic method in which moxa is used as a material to directly or indirectly cauterize acupoints on the body surface after being ignited. It can also be mixed with a small amount of pungent, warm, aromatic and dry medicinal powder to enhance the therapeutic effect. The method has the effect of warming the meridians and collaterals, elevating the Yang and lifting up the sinkhole, promoting the circulation of Qi and activating blood circulation, dispelling cold and dampness, eliminating swellings and dispersing knots, and restoring Yang to rescue the reverse and so on, and it can be used for health care. In addition, moxibustion can improve the digestive discomfort and other symptoms of cholangiocarcinoma patients to a certain extent, and can be used as an adjuvant therapy for cholangiocarcinoma symptoms. However, due to individualized differences, it is recommended to be evaluated by a professional physician before making a reasonable choice of whether or not to perform moxibustion therapy. It is worth noting that moxibustion can at most only relieve the symptoms of cholangiocarcinoma, but cannot provide a radical cure. Therefore, once diagnosed with cholangiocarcinoma, patients should go to regular hospitals in time and choose the most reasonable treatment under the guidance of professional doctors to maximize the survival period and quality of life.