The chest pain after drinking alcohol may be related to gastrointestinal diseases, myocardial ischemia, allergies and coronary artery spasm. 1. Alcohol may stimulate the gastrointestinal tract leading to gastrointestinal mucosal damage, causing gastritis and esophagitis and other symptoms, and then chest tightness and pain, you can use some of the gastric mucosal protective agents to temporarily relieve the symptoms, such as aluminum thioglycollate and so on. 2. If the patient himself has coronary heart disease, after drinking a lot of alcohol may induce myocardial ischemia chest pain and other manifestations. 3. People who are allergic to alcohol may experience chest pain after drinking, usually accompanied by skin itching and other symptoms, and even serious and early life-threatening. 4. Some people may experience tachycardia after drinking alcohol which induces coronary artery spasm, which can also cause chest tightness and chest pain. Overall, the chest tightness and pain after drinking is more uncomfortable, should go to the hospital in time to avoid delaying the condition caused by life-threatening.