Infusion ports and PICC tubes have their own advantages and disadvantages, and should be chosen according to treatment needs and individual needs. Infusion port requires surgical operation to cut the local skin and bury the infusion port, which is difficult and traumatic to operate, and the cost is slightly higher. Infusion port buried in the skin, more beautiful, easy to use, does not affect the normal life and work, maintenance time can be up to several years, the risk of thrombosis and infection is also lower, is the best way of treatment for patients with malignant tumors chemotherapy and long-term parenteral nutrition. PICC tube is known as central venous catheter implanted in peripheral vein, mainly used for medium and long term infusion therapy, but the maintenance time is relatively short, patients who need only a few months of intravenous infusion can choose PICC catheterization. the price of PICC tube is lower, the trauma of the catheterization is smaller, the operation and nursing care is relatively simple, and the administration of medication is convenient, but it is easy to lead to infection and thrombosis, and requires more frequent nursing care. It is recommended that patients fully understand the advantages and disadvantages of various infusion methods, and choose the appropriate treatment method in accordance with medical advice.