There is no absolute best medicine, bruise muscle soreness may have caused soft tissue contusion, the choice of drugs include oral drugs (such as Panax ginseng tablets, bruise pills, celecoxib, etc.) or topical drugs (such as Vantone tendon stickers, bruise paste, diclofenac diethylamine emulsion, etc.). 1. Oral medicines (1) Panax ginseng tablets: mainly used for traumatic injuries such as bruises, swelling and pain, with the effect of dispersing blood stasis, subduing swelling, stopping bleeding and fixing pain. (2) Bonesetters Pills: mainly used for bruises, muscle pain, tendon and bone pain, etc., with the effect of promoting qi and activating collaterals, soothing tendons and relieving pain. (3) Celecoxib: a non-steroidal analgesic drug with anti-inflammatory, analgesic and antipyretic effects. 2. External medicine (1) Vantone Tendon and Bone Paste and Bone-setting Cream: it can promote the absorption of localized bruises and has the effect of activating blood circulation and resolving blood stasis to relieve pain. (2) Diclofenac diethylamide emulsion: it belongs to non-steroidal analgesic drugs, mainly used for relieving mild and moderate pain of soft tissues, muscles and joints, such as the pain caused by muscle and soft tissue strains, sprains, contusions and strains. If the symptoms of bruises and muscle pain continue to be unrelieved, it is recommended to go to the hospital in a timely manner, improve the examination and diagnosis, and then follow the doctor’s instructions for regular treatment, not blindly use their own medication. The above medication is recommended to be used under the guidance of a doctor.