Sore throat in adults may be caused by acute tonsillitis, acute epiglottitis, tonsil cancer and other factors, which can be relieved by medication and surgery. 1. Acute tonsillitis: it is acute non-specific inflammation of palatine tonsils, with clinical manifestations of sore throat, fever, difficulty in swallowing and other symptoms. Symptomatic treatments such as antiviral and anti-infection need to be given according to the type of pathogen infection. 2. Acute epiglottitis: most of the cases are acute inflammation caused by bacterial infection, with clinical manifestations of sore throat, dyspnea, cough and other symptoms. Sensitive antibiotics and glucocorticosteroids should be used for symptomatic treatment to prevent laryngeal obstruction. 3. Tonsillar cancer: it is malignant tumor occurring in tonsils, and it is also the most common malignant tumor in oropharynx, which is more common in adults, and it may cause discomfort or pain in throat area. It needs surgical treatment, combined with postoperative radiotherapy and chemotherapy. Adults have a sore throat, should promptly go to the hospital, improve the relevant examination to clarify the cause of the disease, under the guidance of the doctor treatment, avoid unauthorized use of drugs.