Feeling uncomfortable with the tongue clinically there are many kinds of situations, mainly list the common ones for analysis and corresponding treatment. Firstly, if you feel that your tongue is not flexible and comfortable, it may be a central brain disease, such as cerebral stroke, cerebral hardness or cerebral hemorrhage and other related diseases, which may be related to high blood pressure, diabetes mellitus, high blood lipids and other factors, and you need to urgently go to the Department of Neurology for perfecting the cranial CT, cranial magnetic resonance and other related examinations. If you consider cerebral infarction and other causes, you need to apply vasodilator drugs, improve cerebral microcirculation and other appropriate symptomatic treatment, while giving blood lipid, blood pressure and other related treatments. Secondly, the disease of tongue itself, such as tongue ulcer or tongue cancer and other related diseases, the lesion involves the muscles of tongue, resulting in tongue muscle activity restriction, also feel uncomfortable with the tongue, need to do local biopsy to get pathology. If the superficial ulcer is considered benign, it can be treated symptomatically with tablets, and if tongue cancer is considered, it needs to be treated with surgery or postoperative radiotherapy according to the condition. Thirdly, chronic pharyngolaryngitis, long-term dryness of pharynx and foreign body sensation in pharynx lead to dryness of tongue, and it is also easy to have the performance of inflexible tongue movement, and some of the patients can be recovered very soon after being treated with drugs for pharyngolaryngitis in the clinic.