Macroglossia is an acute septic eye disease. Bumps, redness and pain in the eyelids are the typical clinical manifestations of mydriasis. Treatment is achieved clinically through hot compresses, eye drops, and incision and drainage of pus. Treatment of mydriasis may begin with a localized hot compress to promote local blood circulation, help relieve symptoms, and promote the remission of inflammatory flare-ups. Generally, hot compresses can be applied three times a day for fifteen to twenty minutes at a time. Second, antibiotic eye drops or antibiotic eye ointment may be used to suppress the local inflammatory response, control the infection, and help relieve the symptoms. It is recommended to use them four to six times a day. For some patients with early onset mydriasis can take some herbs with clearing and detoxifying function to regulate the body, which can help control the symptoms and prevent the condition from worsening. For patients with wheals that form abscesses, an incision to drain the pus should be made to help control the condition. Clinically, the main incision is made parallel to the eyelid, which reduces the formation of scarring. If the abscess is large, a drainage strip may be placed to achieve drainage. Depending on the patient’s condition, hot compresses, eye drops, oral medications, or incisions to drain the abscess can be used to treat the disease. It is important to pay attention to daily care to avoid recurrence of the disease.