If the disease can be related to the following diseases: 1, infections: various acute and chronic infectious diseases, tuberculosis, sepsis, parasitic diseases: 2, malignant tumors; 3, malnutrition; 4, chronic digestive system diseases; 5, connective tissue diseases, mostly due to persistent or intermittent hyperthermia caused by wasting. 6, endocrine metabolic diseases: such as diabetes mellitus, hypopituitarism, chronic adrenocortical insufficiency, also known as Addison’s disease, (, in addition to wasting, melanin spots on the skin mucosa, saltophilia, hypotension, low fasting glucose, low serum sodium and potassium, some patients have nodular calcifications in the adrenal glands on X-ray). Hyperthyroidism; 7. Anorexia nervosa.