Prenatal check-ups in early pregnancy are necessary not only to detect latent related diseases but also to assess the development of the embryo in the uterine cavity. The following tests are required in the early stages of pregnancy, starting with blood tests such as routine blood, blood group, urine, liver function, kidney function, fasting glucose, coagulation, HIV antibodies, syphilis, hepatitis B and C antibodies and immunological indicators. These indicators are mainly used to assess the health status of pregnant women to avoid the presence of latent diseases that may lead to adverse outcomes of pregnancy. Secondly, gynecological ultrasound is required. Gynecologic ultrasound can not only clarify the location of the fetal sac, but also assess the development of the embryo in the uterus. Therefore, gynecologic ultrasound can initially rule out the possibility of ectopic pregnancy and the possibility of abnormal fetal development. Thirdly, electrocardiogram, echocardiogram, ultrasound of liver, gallbladder, spleen and both kidneys need to be checked. Finally, during the first prenatal checkup, a prenatal checkup health handbook should be established at the obstetrics clinic of the local hospital. This will make the prenatal checkups more systematic and comprehensive. It is convenient for the mother to visit different hospitals, so that the doctor can have a more complete picture of the medical history of the pregnant woman and the results of the preliminary examination. As mentioned above, it is very necessary to seek timely medical checkups in early pregnancy.