In life, due to different age, physical fitness and pressure in life and work environment, some women will experience physical discomfort such as swelling and soreness in the lower back and abdomen when they are first pregnant, especially in advanced maternal age and multiple pregnancies; with the liberalization of the two-child policy and the increase of assisted reproduction (IVF) patients in infertility, the number of advanced maternal age and multiple pregnancies has increased significantly. It is a normal physiological phenomenon, which may be triggered by the early embryonic implantation, uterine ligament pulling, and the change of hormone level in the body leading to accelerated metabolism. It is often manifested as a short period of time, with episodes on both sides of the lower abdomen, aggravated by exertion and relieved by lying down and resting. At this time, we should avoid bending, squatting and other movements, pay attention to maintenance, prevent cold, eat less sour and spicy food, local hot compresses, can be effectively adjusted. If the above symptoms persist for a long time, gradually aggravate, or accompanied by a little vaginal bleeding, do not exclude the possibility of preterm abortion or ectopic pregnancy, need to immediately go to the hospital to recheck blood HCG (human chorionic gonadotropin), early pregnancy ultrasound to clarify; if the blood HCG level is unsatisfactory than the previous increase, early pregnancy ultrasound indicates a normal intrauterine gestational sac, accompanied by intrauterine liquid dark area can be diagnosed preterm abortion, feasible fertility preservation treatment; if the blood HCG value rises, the If the blood HCG value rises and the ultrasound reveals a mass in one of the fallopian tubes without a fetal sac in the uterus, ectopic pregnancy is highly suspected and requires hospitalization for conservative or surgical treatment. Some women may experience back pain in early pregnancy, which is generally mild and short-lived and can be relieved after lying down and resting, and does not affect their work and life, but they should be alert to the possibility of pre-eclampsia and ectopic pregnancy.