As soon as you breathe at night in your sleep your throat seems to be irritated and you keep coughing, there may be reflux pharyngitis, cough variant asthma or allergic pharyngitis. It is recommended to go to the hospital for consultation and treatment according to different diseases. Commonly used medicines are: omeprazole, rabeprazole, salbutamol, meso hydroxy salbutamol aerosol, loratadine, beclomethasone propionate aerosol and so on. 1. Reflux pharyngitis: due to the change of body position at night causes the throat to become sensitive to the stimulation of reflux fluid, thus coughing when breathing. Treatment can use omeprazole, rabeprazole and other drugs that inhibit gastric acid secretion. 2. Cough variant asthma: persistent high airway reactivity and airway inflammation characterized by nocturnal cough. Treatment can be by inhalation with salbutamol or mesylate salbutamol aerosol. 3. Allergic pharyngitis: coughing often occurs due to allergen stimulation. Clinical treatment is often oral loratadine or inhalation of beclomethasone propionate aerosol. If there is any discomfort, consult a doctor in time. Follow the doctor’s instructions to use medication, not private medication.