The cost of a single dose of 13-valent pneumonia vaccine ranges from several hundred to several thousand dollars and should be administered at a regular hospital. The 13-valent pneumonia vaccine is mainly used to prevent infectious diseases caused by 13 serotypes of Streptococcus pneumoniae and is suitable for infants and children between 6 weeks and 15 months of age. If the local consumption level is low and the hospital grade is low, the cost of one injection of 13-valent pneumonia vaccine is usually around several hundred dollars. However, for the 13-valent Pneumonia Vaccine administered in a higher class hospital in a higher consumption level area, the cost of 1 dose is around several thousand dollars. Therefore, the cost of 1 dose of 13-valent Pneumonia Vaccine needs to be judged in conjunction with the area and the grade of the hospital. For 13-valent Pneumonia Vaccine, 3 doses of the vaccine are usually required to be injected on time in order to achieve the desired preventive effect. At present, some infants and children are found to have adverse reactions such as fever, loss of appetite, redness and swelling at the injection site after vaccination. It is recommended to receive the 13-valent pneumonia vaccine at a regular hospital and stay in the hospital for a period of observation after the vaccine is administered, in order to deal with allergies and other abnormalities in a timely manner.