Novel coronavirus pneumonia is isolated at home, and it is possible for asymptomatic infections and mild infections to resolve spontaneously, while severe infections and critically ill infections do not resolve spontaneously. 1. Asymptomatic and mild infections: asymptomatic infections usually have no relevant clinical symptoms, and mild infections have mild clinical symptoms, this part of the patient can be isolated at home, pay attention to drinking plenty of water, and use symptomatic medication, and may be able to cure themselves. 2. Severe and critical infections: patients with severe and critical infections need to be hospitalized, because the clinical symptoms and signs of these patients will progress gradually, with respiratory difficulties, coagulation disorders, acid-base balance disorders, and even multiple organ failure, which need to be hospitalized and treated with reasonable therapies. For patients with new coronavirus pneumonia, it is recommended to consult the Department of Infectious Diseases of regular hospitals to distinguish whether it is possible to isolate them at home, and do not blindly wait for them to recover from the disease. Tip: In this article, the terms “new coronavirus pneumonia” and “new coronavirus pneumonia” were renamed to “new coronavirus infection” on December 26, 2022, as announced by the National Health Commission.