Shoulder pain after waking up is mainly caused by the following conditions: 1. Because of the high activity of the shoulder joint the day before, muscle strain and local inflammation of the fascia occur after exertion, and the inflammatory reaction builds up after the night and reaches its peak in the morning, so you will feel pain in the shoulder joint and have limited activities. This kind of pain is generally easy to treat, after sufficient rest, with hot compresses, massage or oral non-steroidal anti-inflammatory and analgesic drugs, both can achieve the purpose of healing. 2, is the shoulder joint periarthritis, commonly known as periarthritis, fifty shoulder. The history of periarthritis pain is usually long, and the shoulder joint activity is significantly limited. The pain is more intense, showing a degree of stabbing pain or swelling. Treatment is relatively complicated and requires oral non-steroidal anti-inflammatory and analgesic drugs, including topical application of Fotarine ointment.