Positive anti-glomerular basement membrane antibody is mostly due to the body’s immune dysfunction, producing anti-glomerular basement membrane antibody, which often leads to acute glomerulonephritis. When the body is attacked by external substances (such as upper respiratory tract infections, exposure to certain organic chemical solvents, etc.), antibodies against exogenous substances can be produced, and sometimes this can lead to a disorder of the body’s immune function and the production of antibodies against the body’s own tissues, such as anti-glomerular basement membrane antibodies. Anti-glomerular basement membrane antibodies bind to the glomerular basement membrane of the kidney to induce complement activation, which damages the glomerular basement membrane, leading to the pathologic type of acute glomerulonephritis with crescentic nephritis. Sometimes anti-glomerular basement membrane antibodies can also bind to and damage the basement membrane of alveolar capillaries, leading to pulmonary hemorrhagic nephritis syndrome. If you have positive anti-glomerular basement membrane antibodies, you should consult a regular hospital and follow the doctor’s instructions for standardized treatment.