[Abstract] OBJECTIVE: To investigate the clinical value and significance of applying radical vagus nerve preserving gastric cancer treatment in the treatment of gastric cancer. METHODS: Group design was performed according to the random number table method, and 80 patients were divided into study group and control group, 40 cases each, and the clinical efficacy of the two groups were compared after treatment. RESULTS: There was no statistical difference in the operation time and bleeding volume (P>0.05), while the first venting and defecation time was less in the study group than in the control group (P<0.05), and the postoperative complication rate was (5.00%) in the study group and (27.50%) in the control group, with statistically significant differences (P<0.05). CONCLUSION: The application of vagus nerve preserving radical gastric cancer treatment for gastric cancer has precise clinical effects and few complications, so it is recommended to be promoted and applied in all hospitals. In clinical treatment, gastric cancer is a relatively common malignant tumor disease of the gastrointestinal tract, and at present, the incidence of gastric cancer is also on the rise [1], and the clinical treatment mainly applies surgical methods, i.e., radical surgery therapy for gastric cancer, and while applying radical surgery for gastric cancer, it also pays great attention to the safety of surgery, in addition to paying more attention to the function of the patient's residual stomach and digestive organs after surgery, and to the patient's In order to further explore the value and effect of this operation in the treatment of gastric cancer, the author adopted this operation for 80 patients, which is analyzed as follows. 1. Clinical data and methods 1.1 Clinical data The author selected 80 patients with gastric cancer treated in our hospital from January 2012 to February 2014, all of whom received preoperative electronic gastroscopy and were diagnosed with clinical symptoms and signs, and were randomly divided into a study group and a control group of 40 cases each, of which 22 were male and 18 were female, with an average age of 57.2±2.5 years and tumor In the control group, there were 21 males and 19 females with an average age of 57.9±2.8 years, and the tumor sites were analyzed: 15 cases in the lower part of the gastric body and 25 cases in the pylorus of the gastric sinus. There was no statistical difference in age, gender and tumor distribution between the two groups (P>0.05), and they were comparable, and all signed an informed letter before surgery. 1.2 Methods Control group: treated with conventional radical gastric cancer and lymph node dissection at the same time. In the study group, radical surgery for gastric cancer with preservation of the vagus nerve was performed by tracheal intubation. During the operation, the vagus nerve in the small omentum under the left liver was carefully identified, the lower branches were searched for, and the small omentum was severed caudally, and the hepatic branch was preserved. The lymph nodes were cleared by following the common hepatic artery, and then the vagus nerve was tractioned through the posterior cardia to find the vagal branch of the vagus nerve, and the ligature line of the distal position of the left gastric artery was tractioned to the right and tractioned to the left, and the posterior branch and related branches were preserved, and then the surrounding lymph nodes and connective tissue were cleared. 1.3 Observation items Observe the operation time and bleeding volume, the time of first exhaustion and defecation in both groups, and record in detail the postoperative complications in both groups. 1.4 Statistical methods: The operating time, bleeding volume, exhaustion and defecation time were entered into the computer for statistical analysis, and the statistical software used was SPSS16.0. The measurement data were expressed as mean±standard deviation (x±s) by paired t-test, and the count data were expressed as rate by X2 test. 2. Results 2.1 Comparison of surgery-related indexes between the two groups: The surgical indexes of the two groups were observed, including the operation time and bleeding volume, the time of the first exhaustion and defecation, and there was no statistically significant difference between the study group and the control group when comparing the operation time and bleeding volume (P>0.05), but the time of the first exhaustion and defecation of the two groups was less than that of the control group (P<0.05), see Table 1 . 2.2 Comparison of complication rates between the two groups: the main complications of patients in the two groups after surgery were discomfort with meals, habitual diarrhea and bile reflux, etc. In the study group, there was one case of discomfort with meals and one case of habitual diarrhea, with a complication rate of (5.00%), while in the control group, there were four cases of discomfort with meals, three cases of habitual diarrhea and four cases of bile reflux, with a complication rate of (27.50%), comparing the two groups. The difference was statistically significant (X2=33.056, P<0.05). 3, Discussion Currently, it is more common to report many cases in which the vagus nerve is successfully preserved in the clinical application of radical gastric cancer treatment [2]. It also provides a more scientific basis for the wide application of radical surgery for gastric cancer with preservation of the vagus nerve. As a major component of the autonomic nervous system, the vagus nerve is mainly responsible for managing the human gastrointestinal tract, which can effectively induce the pancreas to secrete pancreatic juice and can better regulate intestinal peristalsis to prevent the occurrence of abdominal distension. The nerve tissue of human internal organs can wrap the left gastric artery, the common hepatic artery and the celiac artery, and the peripheral lymph nodes are all on the outside of the vascular nerve tegument and arranged in a laminar pattern, so it is feasible to perform lymph node dissection and preserve the nerve, and it will not adversely affect the efficacy of radical surgery. In this study, the application of vagus nerve preserving radical surgery for gastric cancer achieved more significant clinical efficacy, and after treatment, the patients in the study group had less time to first exhaustion and defecation than the control group, and the difference was statistically significant, and the incidence of postoperative complications was also significantly lower than that of the control group, and the results of this study were consistent with the reports in the relevant literature [3-4]. Radical vagus nerve-preserving gastric cancer surgery as a reduction surgery has the advantages of safety, less invasive and significant radical effect, which can stabilize the gastrointestinal microenvironment of patients to the greatest extent and can significantly reduce the postoperative complication rate of patients and improve their quality of life at the same time, but the operation of this procedure is difficult and must be operated by experienced surgeons, and for now, the safety and oncological However, this procedure is difficult to perform and must be performed by experienced surgeons. In conclusion, the application of vagus nerve preserving radical gastric cancer treatment for gastric cancer is a more ideal procedure for the clinical treatment of gastric cancer, which meets the requirements of modern surgery and is recommended to be promoted.