Two cycles of chemotherapy will cause some damage to the body, but it is not easy to assess the size of the specific damage, as everyone has different tolerance, and the damage caused mainly includes bone marrow suppression, mucous membrane damage, gastrointestinal tract dysfunction, liver and kidney function abnormalities, and allergic reactions. 1. Bone marrow suppression: chemotherapy may affect bone marrow hematopoiesis, which may further lead to a decrease in blood cells, especially white blood cells. 2. Mucous membrane damage: the application of chemotherapeutic drugs may easily cause damage to the mucous membrane, especially mouth ulcers. 3. Gastrointestinal disorders: chemotherapy can affect the functional status of the digestive system, leading to gastrointestinal disorders, causing indigestion, nausea, vomiting, etc. 4. Abnormalities of liver and kidney functions: the use of drugs may affect the liver and kidney functions, resulting in abnormal liver and kidney functions, and in severe cases, may even lead to renal failure. 5. Allergic reaction: the use of drugs may lead to allergic reactions, appearing all over the body multiple rashes and a series of manifestations. Physical damage during chemotherapy requires timely medical observation for evaluation and standardized care under the guidance of clinicians to prevent serious physical damage.