Ibuprofen extended-release capsules and amoxicillin are two very different medications, ibuprofen extended-release capsules are one of a variety of non-steroidal anti-inflammatory drugs, while amoxicillin is one of the penicillin antibiotics, used together they can provide antipyretic and analgesic, anti-inflammatory and antibacterial effects. Ibuprofen extended-release capsules are composed of ibuprofen, which is one of the NSAIDs, and extended-release refers to the slow release of the drug after it enters the digestive tract, and capsules are the dosage form. Therefore, ibuprofen extended-release capsules have antipyretic and analgesic, anti-inflammatory effects. Amoxicillin is one of the penicillin antibiotics, which has a good antibacterial effect on a variety of bacteria, spirochetes and other pathogens, and is widely used in upper respiratory tract infections, urinary tract infections and other diseases caused by pathogens, which have a better therapeutic effect. The simultaneous use of the two drugs is usually for infectious diseases with fever, amoxicillin for the cause of the infection for treatment, ibuprofen extended-release capsules for fever symptomatic treatment. Drugs need to be used under the guidance of a physician, after the use of any discomfort to the regular hospital in time.