The cranium is a strong bone in the human head, which plays an important role in human life, not only to ensure the integrity of the skull at all times, but also to maintain normal intracranial pressure and a stable intracranial environment. However, in reality, there are many unforeseen accidents that cause many people to suffer from cranial defects. The neurosurgical guidelines clearly state that cranial defects of 3cm*3cm or more should be repaired as soon as possible when the patient’s condition is stabilized. Although cranial bone repair surgery in most general hospitals can be carried out, but because the operation involves the human scalp, blood vessels, brain tissue, nerves and other important organs, but also found that there are patients with postoperative rejection of infection and other complications, so the patient should not be taken lightly, we must choose the advanced and mature cranial bone repair technology. It is reported that polyether ether ketone peek cranial bone repair, with new high science molecular peek do implant material, take embedded repair way, smooth articulation after surgery, strong resistance to hit, low rejection infection rate. At the same time, we carry out personalized optimal design of the material and the innovation and upgrading of the surgical technology, introducing the concept of cosmetic plastic surgery, and formulate personalized cranial bone repair and cosmetic plastic surgery plan for each patient to ensure the precise postoperative repair and the symmetry of both sides of the shape is natural and beautiful. In fact, the specific cost of PEEK material cranial bone repair surgery also needs to be based on the size of the patient’s defect area, the difficulty of the operation, the presence of other comorbidities, specific treatment and care and other factors to be considered. Patients with cranial defects do not need to worry, and it is recommended that patients go to a regular hospital to repair their skulls as soon as possible.