Patient: 31 years old, male, 57 KG, aortic insufficiency was found by accidental ultrasound in June this year. Ultrasound diagnosis description: functional diastasis of the aortic valve with moderate – severe insufficiency of closure and slightly thickened ventricular septum. 1. Is there still several approaches to aortic replacement surgery (traditional full sternal opening, opening of two ribs, small axillary and extra-axillary chest incisions, etc.)? What are the disadvantages of each approach? 2. Which method is mainly used in your hospital? 3. What is the total cost? What is the approximate cost of imported flaps and related equipment? What is the approximate retail price of imported Warfarin? What is the daily dose? Thank you! Wuhan Union Hospital Cardiac Surgery Department Xia Jiahong Wuhan Union Hospital Cardiac Surgery Department Xia Jiahong: I don’t know if you have already seen our clinic. Based on the brief information you provided, I suggest you to have the surgery as early as possible. The surgery is very mature, doing a conventional chest incision, both domestic and imported valves are available, and the cost of the surgery ranges from 30,000 to 50,000 yuan. The full cost of an imported valve replacement is about$50,000. We currently recommend that patients take domestic warfarin because we can guarantee a year-round supply of the drug. Imported warfarin is often out of stock. The dose is about 1 tablet per day, but nevertheless the indicator of blood check. I wish you a speedy recovery.