The side effects of buspirone hydrochloride are relatively small, especially as an anti-anxiety drug compared to benzodiazepines, there is no dependence, that is, no addiction to long-term use, which is the biggest difference, and is particularly safe. Some patients may experience gastrointestinal reactions, such as nausea, vomiting or constipation, and a few patients may experience dizziness, headache, sweating or palpitations, but the likelihood is relatively small. If the drug is taken for a long period of time, it is necessary to consider that buspirone hydrochloride may cause abnormal liver and kidney functions, for example, this drug needs to be metabolized by the liver and excreted by the kidneys, so if the drug is taken for 3 months or more, the liver and kidney functions should be checked regularly, especially in patients with serious liver and kidney diseases, and the use of the drug may be prohibited.