The soles of the feet by mosquito bites red, swollen and hard lumps can be relieved by general treatment, topical medication, oral medication, etc.; if there is a serious pus, follow the doctor’s instructions to apply antibiotics and other treatments. Plantar mosquito bites appear red, swollen and hard, can be used externally with ice and other cold compresses, need to pay attention to the ice needs to be wrapped in a towel to prevent frostbite. You can also use glycerin lotion under the guidance of a doctor to apply wet compresses, to astringent, itching, swelling and so on. If the local edema is serious, you can follow the doctor’s instructions to use mometasone furoate and other glucocorticoid ointment as appropriate. If the patient has itching symptoms, external drugs can not be relieved, but also comply with the doctor’s prescription oral loratadine, cetirizine and other antihistamines anti-allergy treatment; when the symptoms are serious, but also comply with the doctor’s prescription oral prednisone and other glucocorticosteroid drugs. If the patient scratching combined with bacterial infection, causing cellulitis, need to consult a doctor in time, under the guidance of the use of cephalosporin antibiotics and other anti-infective treatment, if the local fluctuation of sensation, but also need to incise and drain. It is recommended that patients with red, swollen and hard lumps on the soles of their feet from mosquito bites go to the hospital in a timely manner, and standardize the treatment under the guidance of the doctor.