The difference between Mafolone and Eusemide is that they are both short-acting contraceptives. However, Mafron is a third-generation short-acting contraceptive, while Eusemide is a fourth-generation short-acting contraceptive, meaning that Eusemide is a step up from the original pill. The progestin in Eusemide is the more advanced drospirenone, which clinically prevents water and sodium retention and does not cause fattening side effects. In contrast, MaFuLong may clinically cause weight gain and sodium retention after oral administration, which is the difference between MaFuLong and Eusebio. Both are taken orally starting on the 5th day of menstruation, once/day, 1 tablet/dose, for 21 days. It is possible that a small amount of vaginal bleeding may occur during the course of taking the medication. Continue taking it and this bleeding will be improved.