Large arm pain can be relieved through general treatment, medication, physical therapy and surgery depending on the cause. It may be due to overwork, myofasciitis, cervical spondylosis, frozen shoulder and other causes. 1. Overexertion: Because overexertion will cause the accumulation of local lactic acid, resulting in pain in the big arm, which can be relieved after rest. 2. Myofasciitis: Pain caused by myofasciitis can be relieved by hot compresses, massage and other physical therapy, and when the pain is severe, oral ibuprofen, celecoxib and other analgesic medications can be taken. 3. Cervical spondylosis: cervical disc degeneration and protrusion of the nerve roots innervating the upper limbs are compressed, causing pain and numbness in the upper limbs. Avoid prolonged head down and exercise the neck properly. Pain relieving drugs such as ibuprofen and nutritive nerve drugs such as methylcobalamin can be taken orally. Physical therapy such as infrared ray and ultrashort wave can also be used to improve the symptoms. If the conservative treatment is ineffective and the symptoms are serious, anterior or posterior cervical spine surgery is feasible. 4. Frozen shoulder: Frozen shoulder is an inflammation of the soft tissues of the shoulder, commonly found in people around fifty years old. In the acute stage, the shoulder joint should be braked, and non-steroidal painkillers such as Celecoxib can be taken orally, and physical therapy such as acupuncture and massage can also be carried out by professionals. During the recovery period, the shoulder joint should be strengthened to avoid joint adhesion. If conservative treatment is not effective, arthroscopic release surgery may be given. There are many other causes of arm pain, such as trauma, etc. If rest does not relieve, it is recommended to go to the hospital in a timely manner to improve the examination to clarify the cause of the disease, and follow the doctor’s instructions to carry out targeted treatment, do not use their own medication and treatment, so as not to delay the condition.