Usually hormones refer to glucocorticoids, generally speaking, glucocorticoids are considered long-term when used for 3 months. Some autoimmune diseases, renal disease, adrenal replacement therapy requires long-term application of glucocorticoids, such as systemic lupus erythematosus, dry syndrome, dermatomyositis, nephrotic syndrome, hypoadrenocorticism. Some shock, allergy, etc. are short-term applications, such as anaphylaxis, toxic shock, atopic dermatitis, and so on. Generally 3 months is considered a long-term application. Higher doses or long-term use of this product may cause diabetes, high blood pressure, infections, peptic ulcers or bleeding, osteoporosis, and Cushing’s syndrome-like symptoms such as full-moon face and buffalo back, and may also produce psychiatric symptoms such as depression. Glucocorticosteroids should be used under medical supervision and should not be used on their own to avoid serious adverse effects.