There are pathological and non-pathological causes of bone calcification, and it is important to distinguish between them in clinical practice. If the cause is pathological, such as hyperparathyroidism or renal osteodystrophy, treatment should be directed at the primary disease. If the non-pathological bone calcification, i.e. osteophytes, occurs with age, the patient has more obvious pain and other discomfort symptoms, treatment should be based on the patient’s symptoms to take symptomatic treatment such as pain relief, drugs can be applied externally cream or oral non-steroidal anti-inflammatory drugs. If the patient has severe lesions, pain is intolerable or there is a skeletal deformity of the joint, surgical treatment is required, such as deformity or pain in the weight-bearing part of the knee joint, which can no longer be weight-bearing, and artificial joint replacement or other surgical interventions are required. For patients who do not have indications for surgery but need to relieve their symptoms, local injections of sodium vitrate can also be used. Therefore, patients with osteochondral calcification are treated differently and treated according to their specific condition and analysis of the specific causes of the disease.