Ammonia is present in the urine, so there is an ammonia odor in itself, so usually a strong, strange odor from one’s urine is normal. However, if the symptom has only appeared recently, it may be related to drinking too little water, dietary factors, medication factors, urinary tract infections, diabetes, liver failure and other reasons. When there are disease factors, should be timely treatment with medication, control the development of the disease, and good care. 1, too little water: too little water for a long time, will make the urine concentration, then the water content in the urine is reduced, the content of other substances increased, can lead to their own urine has a strong strange smell, should increase the amount of water, increase urination, usually able to autonomously recover; 2, dietary factors: such as a large number of eating Protein-rich foods, protein in the metabolic process will produce sulfur compounds, through the urinary discharge, there can be a strong smell of their urine, mainly sulfur odor, generally no other symptoms, can be adjusted through the diet, and gradually improve the situation; 3, drug factors: often take sulfonamides and B vitamins and other drugs, the metabolism of the substances produced by the easy to show a significant odor The drug can make one’s urine have a strong and strange odor. Generally under the guidance of a doctor, safe to stop using drugs, can gradually return to normal; 4, urinary tract infections: for example, cystitis, due to local infected parts of the inflammatory material is more, accumulated in the urine, can lead to their own urine has a strong smell, but also accompanied by pain in urination, urinary frequency and other symptoms, and even hematuria. After diagnosis, antibacterial drugs should be used to give treatment, such as roxithromycin capsules, ciprofloxacin hydrochloride tablets, etc.; 5, diabetes mellitus: this kind of patients due to high blood glucose, there will be urine ketone body high situation, may make their urine have a strong smell, should be under the guidance of the doctor application of hypoglycemic drugs to control blood glucose, for example, metformin hydrochloride enteric capsule, akarbose tablets, etc., and if necessary, also need to use the menthyl insulin Injection treatment; 6, liver failure: mainly associated with viral infections, drugs, alcohol and other factors causing liver injury, resulting in liver dysfunction, this time due to abnormal protein metabolism, which can increase the concentration of ammonia in the urine, resulting in a strong strange smell of one’s own urine, but also accompanied by fatigue, jaundice, ascites and other symptoms. Patients should rest in bed to reduce the burden on the body, and should also be given timely nutritional support. Liver-protecting drugs such as compound glycyrrhizin tablets and silymarin capsules can be chosen for treatment. For liver failure caused by viral infection, antiviral drugs such as entecavir dispersible tablets and tenofovir disoproxil fumarate tablets can be chosen for treatment. Treatment such as artificial liver support therapy and liver transplantation should also be considered if necessary.