Hands and feet especially sweaty causes generally have spleen and stomach qi deficiency, yin deficiency, dampness and heat, etc., the specific medication should be prescribed by a professional physician to identify the evidence to decide, commonly used treatments have benefited qi to strengthen the spleen, nourishing yin and clearing heat, clearing heat and dampness. Due to the internal vaporization of dampness and heat in the spleen and stomach and the limbs due to the symptoms of dampness and sweating on the hands and feet, the sweat is yellowish in color and sticky, body weight and drowsiness, bitter taste in the mouth, yellow urine, the treatment should be to clear away the heat and promote dampness, the commonly used medicines are gentian diarrhea and liver soup and so on. Due to prolonged deficiency of the spleen and stomach qi, the spleen yang is weak and cannot warm up the outside, the symptoms are sweaty hands and feet, cold hands and feet, lack of breath and lazy speech (lack of strength, don’t want to talk), tiredness and fatigue, dullness (lack of appetite, reduced food intake), loose stools (thin and unshapely feces), commonly used medicines such as Li-Zhong Pill. Due to the deficiency of Yin in the spleen and stomach, heat is generated from within, disturbing the Yin fluid and forcing the Jin to leak out. Symptoms include sweating of the hands and feet, heat in the heart of the hands and feet, night sweating (sweating abnormally after falling asleep, and sweating stops after waking up), zygomatic redness (reddish color of the cheeks and zygomatic bones), and dryness of the mouth, and the commonly used medicines are Angelica Luk Wong Tang, and so on. When discomfort occurs, one should consult a doctor in time and choose medication under the guidance of physician’s diagnosis, and should not use medication on one’s own in order to avoid delaying the condition.