Vitiligo and ordinary white spots are two different concepts, ordinary white spots including vitiligo, can not judge the two. Vitiligo is a specific skin disease, manifested as a complete loss of pigmentation of the skin lesions, porcelain white spots, white spots of different sizes and patterns, clear borders, edges of the pigmentation, the patient usually have no self-conscious symptoms. The etiology is related to heredity, immune dysfunction, neuroendocrine disorders, and self destruction of melanocytes. White spots are a descriptive diagnosis, there are many reasons for white spots, including vitiligo, halo nevus, white furfury or other diseases, different diseases are different white spots, such as white furfury is mostly incomplete depigmented spots on children’s face, with scales on the surface and fuzzy edges, and halo nevus is a circle of depigmented spots around the nevus. Generally through the clinical experience of dermatologists, most of the vitiligo can be diagnosed, for some atypical performance of the white spots can be through the Wood’s lamp, dermoscopy, skin pathology and other ways to assist in the diagnosis. It is recommended that patients who have white skin, as soon as possible to the regular hospital, clear the cause of the disease, follow the doctor’s instructions standardized treatment.