Thyroid disease may cause symptoms of chest tightness and shortness of breath, most commonly caused by hyperthyroidism, and is also easily accompanied by weight loss, fear of heat, sweating, and can cause proptosis, insomnia, vision loss, emotional agitation, and even anxiety disorders. Generally need to go to the hospital to do a comprehensive examination, mainly do blood routine, thyroid four, thyroid radionuclide examination, need to use anti-thyroid drugs to treat, commonly used drugs are methimazole, propylthiouracil and other drugs, the symptoms are more serious cases also need to be treated surgically. There are other causes of goiter can also compress the airways, causing chest tightness, shortness of breath symptoms, need to be based on the specific situation to do the appropriate tests to actively treat.