A friend asked: Why did the second and fifth tests become positive after the hepatitis B vaccination when all five hepatitis B tests were negative before the hepatitis B vaccination? First of all, we need to determine whether the two tests were performed in the same hospital, with the same kits and methods, because the methods and kits are different, the sensitivity of the tests are different, and the results are different, so we cannot fully compare them. Secondly, it is important to clarify the time after the vaccination. Generally, the test is repeated after one month after the vaccination. I know an example of a person who found all 3 antibodies positive after the vaccination, but only the second one was positive after a year of rechecking. Thirdly, the incubation period of hepatitis B can be up to 6 months, so it is possible that you were already in the incubation period of hepatitis B infection before the vaccination, and then after your own immunity, you entered the recovery period, and there were 2 or 3 positive antibodies. It should also be noted that having 2, 5 or 2, 4, 5 positive hepatitis B items means that you are in the recovery period or have recovered, so you can say that there is no big difference with a healthy person and life, work and study will not be affected. Pay attention to the annual review can be.