Ulcers at the corona of the penis may be caused by diseases such as glansitis, genital herpes, syphilis, etc. Patients can choose the appropriate medication under the guidance of the doctor according to the actual condition. 1. glans: usually due to local irritation, infection and other factors leading to inflammatory lesions of the mucosa of the glans, if not treated in time, may lead to long-term stimulation of inflammation, resulting in penile coronal ulcers. Patients can use anti-inflammatory drugs such as levofloxacin and ceftazidime under the guidance of doctors. 2. genital herpes: usually due to herpes simplex virus infection and other factors leading to sexually transmitted diseases, when the local friction, may lead to epidermal ulceration, resulting in penile coronal ulceration phenomenon. Patients can be treated with medications such as acyclovir and vasiclovir under the guidance of a doctor. 3. Syphilis: usually due to the syphilis spirochete caused by the invasion of multiple systems of chronic sexually transmitted diseases, the disease if not treated in time, may lead to the continued development of the disease, the emergence of penile coronal ulcers phenomenon. The patient can use the big defeat poison capsule, penicillin and other drugs under the guidance of the doctor for treatment. When the patient has a penile coronal ulcer, it can not be ruled out due to warts and other diseases, based on a symptom alone can not determine the specific cause, it is recommended that the patient timely medical examination, and under the guidance of the doctor according to the relevant examination to determine.