Elevated blood glucose may cause peripheral itching, and the causes may be twofold: 1. Elevated blood glucose leads to increased secretion of sebaceous glands and sweat glands, and a large number of sweat glands may have some blockage of the pores. Patients are prone to folliculitis and even acne, which can cause itching.2. Long-term hyperglycemia may produce peripheral neuropathy in diabetes. Peripheral neuropathy may also produce on the body to provide abnormal signals, resulting in the body has a generalized itching sensation, without other clinical manifestations. Patients may experience improvement in peripheral itching while controlling blood glucose, nourishing nerves, and improving microcirculation.