Neonatal jaundice of 20mg/dl for 5 days is serious and needs to be considered as pathologic jaundice, which should be treated aggressively and may lead to complications such as kernel jaundice if not treated aggressively. The jaundice value of newborns 5 days after birth should be less than about 15mg/dl, 20mg/dl needs to be considered as pathologic jaundice, which needs blue light treatment. Pathologic jaundice usually occurs within 24 hours of birth with serum total bilirubin exceeding 15mg/dl. Newborns 5 days after birth for the peak of physiological jaundice in newborns, but usually not more than 15mg/dl, 5 days 20mg/dl has reached the diagnostic criteria for pathological jaundice, the need for blue light irradiation treatment, if necessary, need to change the blood treatment, and do not actively treat the bilirubin encephalopathy can lead to, and even life-threatening. Neonatal jaundice 5 days 20mg/dl, it is recommended that the patient actively consult the doctor, follow the doctor’s instructions for treatment.