Calcification of thyroid nodules may be a benign manifestation or a malignant one, and consultation with a doctor is recommended. Calcification of thyroid nodules is an imaging description that refers to the presence of calcified foci within a thyroid nodule, usually due to calcium deposition, which may be a benign development or a sign of deterioration. Benign thyroid nodules with calcification usually have less impact on the body and can be reviewed regularly as prescribed by the doctor. Malignant calcification of thyroid nodules requires timely consultation with the hospital for definitive diagnosis and active treatment. Patients who have thyroid nodules with calcification should go to the hospital and ask the doctor to make a judgment.