The bladder wall thickening requires further examination to determine how to treat the cause. 1, bladder wall thickening is a secondary change of some diseases, such as urethral stricture, prostatic hyperplasia, urethral stones, etc., because of frequent forceful urination that leads to compensatory bladder wall enlargement, this enlargement needs to deal with the primary disease, after removing the primary cause of bladder wall thickening can be restored, such as surgical treatment of urethral stricture, or prostatic hyperplasia medication or surgery. 2, neurogenic bladder, due to damage to the nerves that govern the bladder, resulting in bladder contraction weakness, the effective capacity of the bladder is reduced. 2, neurogenic bladder, due to damage to the nerves innervating the bladder and resulting in bladder contraction weakness, which over time can easily cause a reduction in effective bladder capacity and bladder wall thickening, which requires nutritional brain cells to treat the primary disease or continuous indwelling catheter drainage to completely improve the bladder wall thickening, which requires further urodynamic testing and cranial CT. 3, the bladder itself appears malignant disease or inflammatory disease, can appear wall thickening, such as the bladder local complications of bladder tumors or bladder polyps can appear local thickening, can also be due to cystitis after the local mucosal muscle edema and lead to wall thickening, then you need to carry out routine urine examination, culture examination and urinary system ultrasound, CT and other examinations to clarify the presence of infectious disease, or the presence of an occupying disease. If infection is present, anti-infective treatment is recommended, either levofloxacin hydrochloride capsules 1 capsule, 3 times daily, orally for 1 week, or intravenous infusion of levofloxacin hydrochloride injection 200 mg, intravenously, twice daily for treatment. If bladder tumors and polyps are present, cystoscopic biopsy and surgical excision are recommended for treatment.