Pioneer Bee, or Cefoperazone Sodium, treats gastritis caused by bacteria such as Escherichia coli, alpha hemolytic streptococcus, and staphylococcus, and is not effective in treating other types of gastric problems. Pioneer Bee, i.e. Cefoperazone Sodium, is a third-generation cephalosporin with good antibacterial effects on Enterobacteriaceae and Pseudomonas aeruginosa, such as Escherichia coli, Klebsiella spp., Aspergillus spp., Salmonella typhimurium, Shigella spp. and Pseudomonas citrobacter spp. It is less effective against Proteus, Enterobacter cloacae, S. typhimurium and Fusobacterium spp. Cefoperazone sodium can be used for infections of the gastrointestinal tract, ear, nose and throat caused by a variety of sensitive bacteria, such as staphylococcus, Escherichia coli, hemolytic streptococcus and other infections caused by acute and chronic gastritis, intestinal inflammation and other diseases. It is important to note that it is contraindicated in patients with allergy to cephalosporins, hepatic insufficiency and biliary obstruction; it should be used with caution in those who are allergic to penicillin. Cefoperazone sodium should be used under the guidance of a doctor and should not be used without authorization.