The so-called hepatitis B blocking shot also refers to hepatitis B immune globulin. For domestic hepatitis B immune globulin, the cost of one 200-unit shot is about 300 yuan. Depending on the location and the manufacturer, the price may vary. There is also an imported hepatitis B immunoglobulin, which is more expensive, usually about 1,000 yuan. Hepatitis B immune globulin is mainly used for acute infection with the hepatitis B virus or as a mother-to-child blockade for hepatitis B. The infant needs to be vaccinated within 24 hours of birth. Infants need to be vaccinated within 24 hours of birth, and adults infected with the hepatitis B virus also need to be vaccinated within 24 hours.