Thyroid peroxidase should refer to anti-thyroid peroxidase antibody (TPOAb), thyroid stimulating hormone and high TPOAb may suggest that there is Hashimoto’s thyroiditis, etc. It is not yet possible to diagnose the type of disease, and it is necessary to combine with the other results of the thyroid function and the thyroid ultrasound to make a definite diagnosis. A high TSH with normal T3 and T4 may indicate subclinical hypothyroidism. If TSH is high and T3 and T4 are low, it suggests possible hypothyroidism. If TSH is high and T3 and T4 are high, possible pituitary hyperthyroidism. Elevated TPOAb suggests the possibility of Hashimoto’s thyroiditis, or Graves’ disease, among other conditions. Therefore, the simultaneous increase of TSH and TPOAb may suggest the presence of Hashimoto’s thyroiditis, primary hypothyroidism, etc. The type of disease cannot be diagnosed, and it is necessary to combine with other results of thyroid function and thyroid ultrasound to make a clear diagnosis. It is recommended that the patient consult a doctor in time and have the thyroid function checked regularly.