A 44-year-old woman’s knee joint hurts a little when she walks up the stairs may be caused by osteophytes, strained ligaments, and osteoarthritis of the knee joint. 1. Osteomalacia: mainly with age, the joints have degenerated, the cartilage of the joints have been worn out, the joint space has become narrower, the edge of the bone cumbersome formation. Going up the stairs will aggravate the stress on the joints and cause pain. 2. Ligament strain: After ligament strain, going up the stairs will cause the ligaments to be pulled and cause pain, or even aggravate the pain. 3. Osteoarthritis of the knee: a sterile inflammatory reaction that erodes cartilage and causes pain due to synovial membrane congestion and edema. The pain will be more pronounced when the pressure on the knee joint increases when going upstairs. There may be other reasons why a 44-year-old woman’s knee hurts a little when going up stairs, and if the symptoms persist or worsen, it is recommended to go to the hospital in time, under the guidance of the doctor for targeted treatment.