When the ki67 value is different between two pathological results, it is necessary to determine whether the error is caused by different sampling sites or different testing organizations, and it is necessary to ensure that the two sampling sites are the same and the testing organizations are the same. 1. Different sampling sites: ki67 reflects the growth of tumor, mainly counts the local cells seen under the microscope after sampling, which may be affected by the sampling site, immunohistochemistry effect and counting method, if the two sampling sites are different, it will lead to different pathological results, which will easily affect the clinical judgement of the effect before and after the treatment, and then it is necessary to take samples again for testing. 2. Different monitoring institutions: Ki67 can determine the degree of tumor malignancy, assess the prognosis of patients, and determine whether the patients are sensitive to chemotherapy. ki67 preparation method and counting method are related to the testing institutions, so attention should be paid to choosing the same testing institution for measurement, so as not to cause psychological panic or over-treatment of patients. If there is any discomfort, you should consult a professional doctor for treatment.