24-hour urine protein quantitative 2.6g, suggesting proteinuria, may be acute glomerulonephritis, membranous nephropathy, diabetic nephropathy and other diseases. 1. Acute glomerulonephritis: this disease is mainly caused by streptococcal infection, which can occur after upper respiratory tract infection, skin infection, mostly acute onset, with proteinuria, hematuria, edema, hypertension and other major manifestations. 2. Membranous nephropathy: Membranous nephropathy is mainly characterized by the deposition of immune complexes on the outside of glomerular basement membrane and under the epithelial cells with diffuse thickening of the glomerular basement membrane, and most of the patients are manifested with nephrotic syndrome, i.e., proteinuria, hypoproteinemia, edema, and hyperlipidemia. 3. Diabetic nephropathy: diabetic nephropathy is one of the most common microvascular complications of diabetes. If the disease progresses more seriously, the 24h urine protein quantification may also be as high as 2.6g. 24h urine protein quantitative 2.6g may also have other reasons, it is recommended that the patient to the hospital in time, under the guidance of a professional physician to clarify the specific causes of the disease, timely treatment.