Clinical studies have shown that the success rate of second generation IVF is around 30~50%. The quality of embryos is related to the patient’s age, the quality of sperm and eggs, the uterine environment and other factors, so it is not possible to generalize. Second generation IVF is cytoplasmic monosperm injection, in which the male semen is removed from the body, washed and processed, and then the sperm is injected directly into the cytoplasm of the female egg cell, leading to passive fertilization. The embryo is then transferred back into the woman’s uterine cavity to await implantation of a pregnancy. The success rate is higher for patients in better health and lower for those in poorer health. The quality of embryos is better when the patient is younger, the development of sperm and eggs is normal, and the environment of the woman’s uterine lining is more stable, while the quality of embryos is worse when the patient is in an advanced state of life, with a low sperm count, poorly-developed eggs, and a thin uterine lining. If you need to carry out the second generation of IVF, it is recommended to go to the hospital in time, under the guidance of the doctor to clarify the success rate and the quality of embryos according to the individual situation.