Skin feeling bugs crawling and itchy may be considered scabies infection or diabetic peripheral neuropathy caused by the use of sulfur ointment, loratadine, methylcobalamin and other drugs, according to the different situations need to be dealt with. 1. Scabies infection: an infectious disease of the scabies mite parasitized on human skin, manifested by pimples, intense itching at night, mostly occurring in the finger cracks, groin, etc., the skin may also have a raised line. Treatment is based on topical drugs such as 10% sulfur ointment applied morning and evening, contact with clothing and bedding high temperature ironing disinfection, itching intolerable when oral loratadine. 2. Diabetic peripheral neuropathy: diabetes-induced peripheral neuropathy will also appear to feel bugs crawling and itchy performance. In this case, we need to check the blood sugar and glycated hemoglobin, use insulin and other medications, but also can take methylcobalamin nutrition nerve to improve the symptoms. There is no obvious reason for the skin to feel different, it is recommended to go to the hospital to clarify the cause, symptomatic treatment, do not blindly use drugs.