The red rash on the inner thighs, which is painful when touched, may be related to herpes zoster, contact dermatitis, and folliculitis, which require antiviral, antiallergic, and anti-inflammatory medications, respectively. 1. Herpes zoster is a viral infection, in the clinic, in addition to the manifestation of small blisters on the surface of the skin, there will also be burning and tingling discomfort, in the treatment of first of all, we need to give antiviral drugs (acyclovir) treatment, followed by a combination of nutritive drugs (vitamin B1, methylcobalamin) and analgesic drugs (pregabalin, ibuprofen) treatment. 2. Contact dermatitis is a kind of allergic reaction, manifested as local skin erythema, papules, vesicles and blisters, etc., in the treatment of first of all, we should give anti-inflammatory, anti-allergic drugs (compound dexamethasone cream, loratadine tablets), and secondly, we should keep the skin clean, avoid excessive scratching. 3. Folliculitis is a bacterial infectious skin disease, mainly manifested as red follicular papules, pustules, treatment is mainly anti-inflammatory, such as topical mupirocin cream, oral amoxicillin capsules and so on. Due to the different causes of the disease, the treatment is different, the specific situation needs to first ask the doctor for an interview.