Obesity is not only a disease in itself, but also a danger because it can cause many complications and pose different degrees of threat to our health. However, most of the obese people themselves do not know how these complications are caused, because the body does not have obvious abnormalities when the complications do not appear, so most of them do not pay too much attention to these complications. Obesity causes complications can be roughly divided into two ways, one is too much fat directly on the body to cause negative effects, such as hypertension, high blood fat, sleep apnea syndrome. Take hypertension as an example, obese people will become more demanding on blood circulation due to their body size, and the total amount of blood will be more, resulting in an increase in the amount of blood discharged into the arteries per minute, making blood pressure higher. Another way to cause concomitant diseases is to have too many fat cells causing endocrine disorders, more typically diabetes, polycystic ovary syndrome, etc. Our fat not only secretes hormones, but also participates in many inflammatory responses, keeping the body in a state of balance. Moreover, the two ways also affect each other and make the condition more serious, for example, because of the increased insulin resistance, the pancreas needs to secrete more insulin in order to regulate blood sugar, but the high level of insulin in the blood will cause vasoconstriction and make hypertension more serious. Most diseases caused by obesity have a developmental process, so the sooner you lose weight the better for your health, and as we get older, it becomes easier and easier to get fat, but harder and harder to lose weight. Based on the more than 1,000 metabolic weight loss surgeries I have performed, sleeve gastric surgery alone may not be sufficient for long-term weight loss in people over 35 years of age, and needs to be combined with jejunostomy or direct gastric bypass, which can limit absorption, for more optimal results.