Pacemaker surgery available after Parkinson’s disease “honeymoon” period of drugs

Recently, Mr. Zheng, a citizen of Xi’an, gradually became flexible in his limbs after the brain pacemaker was switched on, and excitedly performed boxing and high leg raising movements for the medical staff on the scene, his joy was overflowing. It is understood that Mr. Zheng, 53 years old, has been suffering from Parkinson’s disease for nearly 10 years, with trembling limbs, stiffness, slow movement and emotional depression, bringing him both physical and psychological torture. Mr. Zheng said that in 2008, his pinky joint became stiff, initially thought it was just due to work strain, did not care, and then the symptoms developed from the left limb tremors to bilateral, and finally in 2009 was diagnosed as “Parkinson’s disease”, under the guidance of the doctor began to take Medobar, Antan and other drugs. The symptoms were better controlled at the beginning of the medication, but the development of the disease accelerated after 2014, and the effective time of the medication was significantly shortened, with more serious isokinetic and switching phenomena. In August this year, Mr. Zheng went to a hospital neurosurgery department and underwent brain pacemaker surgery after detailed preoperative examination and evaluation. After the pacemaker was turned on, Mr. Zheng’s originally trembling and stiff limbs became flexible, “I feel very good now, my body is free all of a sudden, my movements are numb, and I don’t shake as much as before, I feel alive again! ……” said Mr. Zheng excitedly. “The effectiveness of brain pacemaker surgery requires a clear diagnosis of Parkinson’s disease, correct target selection, precise electrode placement, appropriate combination of program-controlled parameters, reasonable combination of Parkinson’s disease drugs and proper timing of brain pacemaker surgery.” Professor Wang Xuelian of the Department of Neurosurgery at Tangdu Hospital of the Air Force Medical University said. Parkinson’s disease can be divided into five stages according to the progression of symptoms: Stage 1: unilateral lesions only, unilateral hand tremor, foot tremor or stiffness, walking is not as sharp as usual, holding things unstable; Stage 2: bilateral mild lesions, from unilateral lesions to bilateral, shaking hands, or even whole body shaking, stiffness aggravated, buttoning, holding chopsticks and other daily activities become difficult, poor sense of balance; Stage 3: bilateral lesions with early balance disorders. Difficulty in lifting legs, walking in small steps, easy to fall. Stage IV: severe lesions, often unconscious drooling, difficulty in swallowing and slow eating. Speech is slurred, expression is dull, face is expressionless, movement is difficult, and daily life is inseparable from family care; Stage V: Patients are confined to bed or wheelchair and cannot take care of themselves completely, some patients are only bedridden for a long time and cannot turn over on their own after being bedridden, and cannot take care of themselves completely in daily life. Parkinson’s disease is a chronic progressive disease and the timing of surgery is particularly important. Surgery is most appropriate after the honeymoon period of medication and when motor complications arise, which means that surgery is best when the disease has progressed to “stage 3”. Careful selection of patients with Parkinson’s disease in the early stages of the disease who have just developed motor complications will help to maximize the long-term benefits of pacemaker therapy, after a team of physicians has fully evaluated the pros and cons of the patient.

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