After being pricked by a needle from a patient with hepatitis B, if you lack hepatitis B surface antibodies, you should be immunized with hepatitis B immune globulin and hepatitis B vaccine immediately and try to complete the vaccination within 12 hours. There is a risk of contracting the hepatitis B virus after being pricked by a needle from a hepatitis B patient. If one’s own Hepatitis B surface antibody is less than 10 mIU/ml, or if one’s own Hepatitis B surface antibody level is unknown. In this case, you should immediately receive 200~400IU of hepatitis B immunoglobulin and a shot of hepatitis B vaccine at a different site, both of which should be completed within 12 hours. If after being stabbed by a patient with hepatitis B, one has been vaccinated with hepatitis B vaccine and one’s hepatitis B surface antibody level is known to be more than 10 mIU/ml, in this case it is not necessary to get vaccinated with hepatitis B vaccine and hepatitis B immune globulin due to the existence of autoimmunity.