Intrarectal administration has few side effects and is relatively safe. The main principle is that the drug is absorbed into the bloodstream through the venous plexus of the rectum after it is inserted into the anus, which is more effective and easier to accept, with fewer side effects. The most commonly used drug is indomethacin, which is more effective for children with fever. But pay attention to the dosage, do not overdose, overdose may cause patients dehydration and liver damage, and do not use the drug for a long time. If the patient has fever, it is necessary to find out the cause of the fever, whether it is acute pharyngitis, a cold causing fever, or pneumonia, and then draw blood for routine blood tests after finding out the cause. If there is a combination of abnormal elevation of white blood cells and neutrophils, active anti-inflammatory treatment with antibacterial drugs is required if necessary. If the fever exceeds 39 degrees Celsius, active anti-inflammatory treatment with cephalosporin or macrolide antibiotics is required. Also, if necessary, consider intravenous or intramuscular injection of lysergic acid and other drugs to actively reduce the temperature.